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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABL2
All Species:
36.36
Human Site:
S456
Identified Species:
72.73
UniProt:
P42684
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42684
NP_001093578.1
1182
128343
S456
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Chimpanzee
Pan troglodytes
XP_001156169
1182
128389
S456
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Rhesus Macaque
Macaca mulatta
XP_001115453
1182
128030
S456
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Dog
Lupus familis
XP_537174
1169
126779
S443
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4JIM5
1182
128178
S456
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Rat
Rattus norvegicus
NP_001100656
1208
131452
S454
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515903
1140
123564
S419
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Chicken
Gallus gallus
XP_422269
1134
124028
S419
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Frog
Xenopus laevis
NP_001084399
1102
120702
D416
N
H
V
V
K
V
A
D
F
G
L
S
R
L
M
Zebra Danio
Brachydanio rerio
NP_001116177
1135
123693
S414
I
K
W
T
A
P
E
S
L
A
Y
N
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P00522
1620
171570
G539
I
K
W
T
A
P
E
G
L
A
Y
N
K
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P03949
1224
138308
G479
I
K
W
T
A
P
E
G
L
A
F
N
T
F
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
96.3
94.2
N.A.
94.6
89.3
N.A.
84.4
83.6
70.8
68
N.A.
34.8
N.A.
32.1
N.A.
Protein Similarity:
100
99.8
97.7
94.9
N.A.
96
90.7
N.A.
88.2
87.5
79
76
N.A.
46.4
N.A.
48.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
100
N.A.
86.6
N.A.
86.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
100
N.A.
86.6
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
92
0
9
0
0
92
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
9
0
0
92
0
% F
% Gly:
0
0
0
0
0
0
0
17
0
9
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
92
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
92
0
0
9
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
92
0
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
92
0
0
0
% N
% Pro:
0
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
0
0
0
9
0
0
92
% S
% Thr:
0
0
0
92
0
0
0
0
0
0
0
0
84
0
0
% T
% Val:
0
0
9
9
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _